resolution of phenylethylamine

Introduction

Most compounds containing an asymmetric carbon are known to be chiral (non-symmetrical) or dissymmetric, and can exist as two mirror image isomers known as enantiomers1. The only difference amidst enantiomers of the same compound is that they rotate the plane of polarized light in equal but opposite directions, designated as (+) and (-)1. A racemic kind is one that contains equal amounts of both enantiomers, which has an overall optical bodily process of 01. The purpose of this experiment is to obtain pure enantiomers from their racemic mixture by treating the racemic mixture with a dissymmetric acid and obtaining diastereomeric table salts. This is known as settle a racemic mixture1. The theory behind this is that the diastereomeric salts have diametric sensual properties, and finding a solvent in which one salt is less oil-soluble than the new(prenominal), we can allow the less soluble salt to crystallize out of the solution to separate it from the to a greater extent soluble salt.
This experiment will also make exercising of a separatory funnel, which is used to separate the layers of molecules based on different densities, which can be extracted separately using the stop-cock as a drain. It will be used in this experiment to sequestrate our desired compound in the end.

Results and Calculations

(-)-amine-(+)-hydrogen tartrate(-)-α-phenylethylamine
Percent Yield75.3%93.



54%
spy RotationN/A-28.38°
Optical PurityN/A71.7%


% Yield of (-)-amine-(+)-hydrogen tartrate

Molar Mass Tartaric caustic = 150.09g/mol3

Molar Mass of (-)-amine-(+)-hydrogen tartrate = 271g/mol

Half the tartaric acid reacts to get under ones skin one diastereomeric salt and the other half reacts to produce the other diastereomeric salt. However, we are only concerned with one diastereomeric salt, which is formed from half the tartaric acid.

½ n acid = n tartrate
½ * 11.9g/150.09g/mol = n tartrate
n tartrate = 0.0396 mol

mass tartrate = 0.0396 mol * 271 g/mol
mass tartrate = 10.73g =...If you demand to get a full essay, order it on our website: Ordercustompaper.com



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